Doxofylline theophylline
WebOct 19, 2024 · Theophylline has two distinct actions in the airways of patients with reversible obstruction: smooth muscle relaxation (i.e., bronchodilation) and suppression of the response of the airways to stimuli (i.e., non-bronchodilator prophylactic effects). WebSep 21, 2024 · Theophylline is a drug derived from methylxanthine (a purine derivative) and has smooth muscle relaxant, bronchial dilation, diuretic, cardiac and central nervous system (CNS) stimulant activities. It is naturally present in small amounts in tea and cocoa beans and was initially extracted and synthesized in 1895 and used as a diuretic.
Doxofylline theophylline
Did you know?
WebTheophylline is typically used more often in dogs than cats, given variable efficacy and, perhaps, less need for chronic bronchodilator therapy in cats. The recommended dose of sustained-release theophylline in cats is 20 to 25 mg/kg PO Q 24 H in the evening (ie, one 100-mg tablet/cat/day). WebFeb 10, 2024 · A literature review by Rogliani et al indicated that, compared with theophylline, the methylxanthine doxofylline is a safer and more effective asthma …
WebOct 27, 2024 · Theophylline has been widely used to treat asthma and COPD since the 1930s, but while effective, it is a drug having a narrow therapeutic window and also many … WebJan 27, 2024 · Theophylline Comparison of Efficacy and Safety of Theophylline, Doxophylline and Acebrophylline as an Add-On in the Management of Chronic Obstructive Pulmonary Disease January 2024 Journal of...
Doxofylline (also known as doxophylline) is a phosphodiesterase inhibiting bronchodilator used in the treatment of chronic respiratory diseases such as asthma and COPD. Like theophylline, it is a xanthine derivative. See more Doxophylline is used to treat chronic respiratory diseases such as asthma and COPD. In animal and human studies, it has shown similar efficacy to theophylline but with significantly fewer … See more Unlike other xanthines, doxofylline lacks any significant affinity for adenosine receptors and does not produce stimulant effects. This suggests that its antiasthmatic effects are mediated by another mechanism, perhaps its actions on See more • Shukla D, Chakraborty S, Singh S, Mishra B (October 2009). "Doxofylline: a promising methylxanthine derivative for the treatment of asthma and chronic obstructive pulmonary disease". Expert Opinion on Pharmacotherapy. 10 (14): 2343–56. See more It is marketed under many brand names worldwide, including: Xiva, An Li Nuo Er, An Sai Ma, Ansimar, Asima, Bestofyline, Chuan Ning, D-Fyal, Dilatair, Doxiba, Doxiva, Doxobid, Doxobron, Doxofilina, Doxofillina, Doxofyllin, Doxoll, Doxophylline, … See more WebThe present study has investigated some pharmacological activities of doxofylline in comparison with theophylline. Doxofylline does not directly inhibit any of the known HDAC enzymes, and did not inhibit any PDE enzyme sub types or act as an antagonist at any of the known adenosine receptors, except for PDE2A(1), and adenosine A(2A) and only at ...
Webtreatment because of adverse events under theophylline than under doxofylline 400 mg t.i.d. (p=0.001). With doxofylline 400 mg t.i.d., the number of patients treated to spare one drop-out due to theophylline was 5. Conclusion: This study provides evidence that doxofylline 400 mg t.i.d. is an effective treatment for reliev-
WebJan 15, 2024 · dyphylline (Dilor) theophylline (Slo-Bid, Theo-Dur) Sympathomimetics albuterol (Proventil) arformoterol (Brovana) ephedrine epinephrine (Sus-Phrine) formoterol (Foradil) indacaterol (Arcapta) isoetharine isoproterenol (Isuprel) levalbuterol (Xopenex) metaproterenol (Alupent) pirbuterol (Maxair) salmeterol (Serevent) terbutaline (Brethaire) prince rupert airport shuttle timesWebTheophylline, also known as 1,3-dimethylxanthine, is a phosphodiesterase inhibiting drug used in therapy for respiratory diseases such as chronic obstructive pulmonary disease (COPD) and asthma under a variety of brand names. As a member of the xanthine family, it bears structural and pharmacological similarity to theobromine and caffeine, and is … prince rupert bc canada weatherWebDec 23, 2024 · Doxofylline is found to undergo hepatic metabolism, which accounts for about 90% of total drug clearance. β-hydroxymethyltheophylline had been detected in the serum and urine after the oral administration of 400 mg Doxophylline given in healthy subjects. The circulating metabolite was found to be devoid of any significant … plenity fsaWebApr 1, 2008 · 2 Doxofylline is a Xanthine molecule that seems to be both Broncho-dilator and Anti-Inflammatory with an enhanced therapeutic window compared to conventional Xanthines such as theophylline and ... prince rupert airport weatherWeb茶碱(theophylline)和多索茶碱(doxofylline)均属于 黄嘌呤的衍生物，常用于支气管哮喘和喘息性支 气管炎缓解期的治疗。 茶碱的最佳治疗窗的血药浓度在10-20 µ g/ml，血 药浓度过大时，不良反应发生率明显上升。 多索茶碱相比茶碱作用较强，起效快，作用时间 长 ... prince rupert bc ferryWebApr 14, 2024 · In this study, multiple spectroscopic and computational methods were utilized to investigate the binding mechanism of doxofylline with lysozyme. The in vitro methods … prince rupert bottle depot hoursWebDescription: Doxofylline, a theophylline derivative, is a bronchodilator. It inhibits phosphodiesterase enzymes which increase cyclic adenine monophosphate (cAMP), … plenity glow study